mamillary bodies การใช้

• In Wernicke's this occurs specifically in the mamillary bodies, medial thalami, tectal plate, and periaqueductal areas.
• Wernicke Korsakoff syndrome in alcoholics particularly is associated with atrophy / infarction of specific regions of the brain, especially the mamillary bodies.
• Frequently, secondary to thiamine deficiency and subsequent cytotoxic edema in Wernicke's encephalopathy, patients will have marked degeneration of the mamillary bodies.
• The medial lemniscus carries axons from most of the body and synapses in the ventral posterolateral nucleus of the thalamus, at the level of the mamillary bodies.
• The mechanism of this degeneration is unknown, but it supports current neurological theory that the mamillary bodies play a role in various " memory circuits " within the brain.
• They bend downward, forming an anterior boundary of the interventricular foramina, become buried behind the wall of the third ventricle and "'end in the mamillary bodies "'".
• It has been argued that the memory impairments can occur as a result of damage along any part of the mamillo-thalamic tract, which explains how WKS can develop in patients with damage exclusively to either the thalamus or the mamillary bodies.
• Brain atrophy associated with WKS occurs in the following regions of the brain : the mamillary bodies, the thalamus, the periaqueductal grey, the walls of the 3rd ventricle, the floor of the 4th ventricle, the cerebellum, and the frontal lobe.
• The amnesia that is associated with this syndrome is a result of the atrophy in the structures of the diencephalon ( the thalamus, hypothalamus and mamillary bodies ), and is similar to amnesia that is presented as a result of other cases of damage to the medial temporal lobe.